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Density

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Reference
Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018-11-29 - 2018-12-12 (experimental phase)
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
air comparison pycnometer (for solids)
Key result
Type:
relative density
Density:
1.31
Temp.:
20 °C

Two tests with different amounts of the test item were performed to determine the relative density D420at a temperature of 20 °C ± 0.01 °C.

Table: Results of the measurement of the density of the test item

Test No.

Temperature [°C]

Amount of test item [g]

Average sample volume [cm³]

Density [g/cm³]*

1

20

4.8588

3.70741

1.31057

2

20

4.7600

3.64880

1.30453

* The pressurizing-expansion cycles are performed until 4 subsequent volume measurements have a relative standard deviation (RSD) of ≤ 0.2 %.

The mean density of the test item at 20 °C was 1.3101 g/cm³. The relative density D420 was calculated by dividing the density of the test item by the density of water at 4 °C (0.9999750 g/cm³).

Conclusions:
relative density (at 20 °C ±0.01 °C): 1.31
Executive summary:

According to OECD Guideline 109 and EU Method A.3., the relative density D420 of the test item 2-Hydroxy-1-[4-(4-(2-hydroxy-2-methylpropionyl)phenoxy)phenyl]-2-methylpropan-1-one at 20 °C ±0.01 °C (compared to water at 4 °C) is D420=1.31.

Description of key information

relative density (determined using EU Method A.3 / OECD 109; GLP): 1.31 at 20 ±0.1 °C (arithmetic mean of two determinations)

Key value for chemical safety assessment

Relative density at 20C:
1.31

Additional information

The relative density of the test material was investigated using a gas comparison pycnometer, designed to be compatible with EU Method A.3 and OECD 109. A reliability score of 1 was assigned, in accordance with the criteria for assigning data quality in line with the principles described by Klimisch (1997).

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