Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-791-5 | CAS number: 126-53-4
Endpoint summary
Administrative data
Description of key information
For the endpoint skin irritation/corrosion there is an in vitro study available (Bisini, 2017) indicative of the fact that Tripelargonine is a non-corrosive substance. In addition there is an acute dermal toxicity study (Salvador, 2014) on the analogue TMP Pelargonate from which there were no indications of skin irritating effects. Based on these studies the substance Neopentyl Glycol Dipelargonate can be regarded as non-irritating to the skin.
With regard to the eye irritation effects, there are also two studies available. An in vitro ( Geitlinger, 2018) on the substance itself and an in vivo study (Salvador, 2014) on the analogue TMP Pelargonate indicate that the test item, Tripelargonine, has no eye irritating properties.
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin corrosion: in vitro / ex vivo
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because an acute toxicity study by the dermal route does not indicate skin irritation up to the relevant limit dose level (2 000 mg/kg body weight)
- other:
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
For read across justification see at section 13
Justification for classification or non-classification
Skin irritation:
As no skin irritating properties are expected based on the available results, a the substance is not to be classified according to the criteria described in EU Regulation No. 1272/2008 on the Classification, Labelling and Packaging of substance and mixtures (CLP).
Eye irritation
As no effects of eye irritation or eye damage are observed in any of the available studies), the substance is not to be classified according to the criteria described in EU Regulation No. 1272/2008 on the Classification, Labelling and Packaging of Substances and Mixtures (CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
