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Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

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Administrative data

Endpoint:
stability in organic solvents and identity of relevant degradation products
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
13 December 2004 - 27 January 2005
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2005
Report date:
2005

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: CIPAC, MT 181 Solubility in Organic Sovlents, CIPAC Volume H, 1998
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
1-[2-(allyloxy)ethyl-2-(2,4-dichlorophenyl)-1H-imidazolium hydrogen sulphate
EC Number:
261-351-5
EC Name:
1-[2-(allyloxy)ethyl-2-(2,4-dichlorophenyl)-1H-imidazolium hydrogen sulphate
Cas Number:
58594-72-2
Molecular formula:
C14H14Cl2N2O.H2O4S
IUPAC Name:
1-[2-(2,4-DICHLOROPHENYL)-2-(PROP-2-EN-1-YLOXY)ETHYL]-1H-IMIDAZOLE SULFATE (1:1)
Test material form:
solid: particulate/powder
Details on test material:
- Product names: FUNGAFLOR® 75C / FUNGAFLOR® 75SP / FUNGAZIL® 750SP / FUNGAFLOR® 75PS / FUNGAZIL® 75SP / FUNGAFLOR® 750SP
- Reference number: JNJ-2634372-ABI / R027180 (product code)
- Physical state: solid
- Appearance: beige solid
Specific details on test material used for the study:
- Batch No.: ZR027180PUH301
- Purity: 99.6% (w/w)
- Expiry date: 18 October 2008
- Storage: at room temperature, in the dark

Results and discussion

Test substance stable:
yes
Transformation products:
not measured

Any other information on results incl. tables

The solubility in n-heptane was below the limit of quantification (10 mg/L). For dichloromethane, acetone and ethyl acetate no difference higher than 12% were found between the relevant samples (72h, 48h and 24h). Therefore, the test item was considered stable in these organic solvents.

For p-xylene a decreasing saturation concentration was observed with increasing observation time. The maximum saturation concentration was measured after incubation time of 6h and 12h. Prolongation of incubation time resulted in lower concentrations. No differences higher than 12% were found between the relevant samples (6h and 12h).

Applicant's summary and conclusion

Conclusions:
The test item is determined to be stable in organic solvents (dichloromethane, acetone and ethyl acetate), except for p-xylene. No degradation products were determined.

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