Registration Dossier
Registration Dossier
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EC number: 261-351-5 | CAS number: 58594-72-2
Stability in organic solvents and identity of relevant degradation products
Administrative data
- Endpoint:
- stability in organic solvents and identity of relevant degradation products
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 13 December 2004 - 27 January 2005
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC, MT 181 Solubility in Organic Sovlents, CIPAC Volume H, 1998
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1-[2-(allyloxy)ethyl-2-(2,4-dichlorophenyl)-1H-imidazolium hydrogen sulphate
- EC Number:
- 261-351-5
- EC Name:
- 1-[2-(allyloxy)ethyl-2-(2,4-dichlorophenyl)-1H-imidazolium hydrogen sulphate
- Cas Number:
- 58594-72-2
- Molecular formula:
- C14H14Cl2N2O.H2O4S
- IUPAC Name:
- 1-[2-(2,4-DICHLOROPHENYL)-2-(PROP-2-EN-1-YLOXY)ETHYL]-1H-IMIDAZOLE SULFATE (1:1)
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Product names: FUNGAFLOR® 75C / FUNGAFLOR® 75SP / FUNGAZIL® 750SP / FUNGAFLOR® 75PS / FUNGAZIL® 75SP / FUNGAFLOR® 750SP
- Reference number: JNJ-2634372-ABI / R027180 (product code)
- Physical state: solid
- Appearance: beige solid
Constituent 1
- Specific details on test material used for the study:
- - Batch No.: ZR027180PUH301
- Purity: 99.6% (w/w)
- Expiry date: 18 October 2008
- Storage: at room temperature, in the dark
Results and discussion
- Test substance stable:
- yes
- Transformation products:
- not measured
Any other information on results incl. tables
The solubility in n-heptane was below the limit of quantification (10 mg/L). For dichloromethane, acetone and ethyl acetate no difference higher than 12% were found between the relevant samples (72h, 48h and 24h). Therefore, the test item was considered stable in these organic solvents.
For p-xylene a decreasing saturation concentration was observed with increasing observation time. The maximum saturation concentration was measured after incubation time of 6h and 12h. Prolongation of incubation time resulted in lower concentrations. No differences higher than 12% were found between the relevant samples (6h and 12h).
Applicant's summary and conclusion
- Conclusions:
- The test item is determined to be stable in organic solvents (dichloromethane, acetone and ethyl acetate), except for p-xylene. No degradation products were determined.
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