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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09 October 2018 to 22 November 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
52 Pa
Key result
Test no.:
#1
Temp.:
25 °C
Vapour pressure:
81 Pa

- The vapour pressure regression curve of the log PT of the test material as function of the reciprocal temperatures was:

log PT = -3389 x 1/T + 13.28 (r = 0.990, n = 8).

 

Table 1: Results of the Vapour Pressure Isothermal TGA Analysis

Temperature (°C)

Weight Loss (µg/min)

VT (g/cm^2/h)

log VT

log PT

PT (Pa)

20

16.2006

1.93x10^-3

-2.71

1.62

42

21.2140

2.53x10^-3

-2.60

1.77

59

30

41.9563

5.01x10^-3

-2.30

2.15

140

36.0801

4.31x10^-3

-2.37

2.06

120

40

83.9153

1.00x10^-2

-2.00

2.53

340

71.5744

8.54x10^-3

-2.07

2.44

280

50

136.652

1.63x10^-2

-1.79

2.80

630

120.697

1.44x10^-2

-1.84

2.73

540

 

Table 2: Vapour Pressure of the Test Material

Temperature (°C)

log PT

PT (Pa)

PT (mm Hg)

20

1.71

52

0.39

25

1.91

81

0.61

Conclusions:
Under the conditions of this study, the vapour pressure of the test material at 20 °C (293 K) was 52 Pa (0.39 mm Hg) and at 25 °C (298 K) was 81 Pa (0.61 mm Hg).
Executive summary:

The vapour pressure of the test material was investigated in accordance with the standardised guidelines OECD 104, EU Method A.4. and OPPTS 830.7950, under GLP conditions.

The isothermal TGA effusion method was applied for the determination of the vapour pressure of the test material.

Under the conditions of this study, the vapour pressure of the test material at 20 °C (293 K) was 52 Pa (0.39 mm Hg) and at 25 °C (298 K) was 81 Pa (0.61 mm Hg).

Description of key information

Under the conditions of this study, the vapour pressure of the test material at 20 °C (293 K) was 52 Pa (0.39 mm Hg) and at 25 °C (298 K) was 81 Pa (0.61 mm Hg).

Key value for chemical safety assessment

Vapour pressure:
81 Pa
at the temperature of:
25 °C

Additional information

The vapour pressure of the test material was investigated in accordance with the standardised guidelines OECD 104, EU Method A.4. and OPPTS 830.7950, under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

The isothermal TGA effusion method was applied for the determination of the vapour pressure of the test material.

Under the conditions of this study, the vapour pressure of the test material at 20 °C (293 K) was 52 Pa (0.39 mm Hg) and at 25 °C (298 K) was 81 Pa (0.61 mm Hg).