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EC number: 916-899-6 | CAS number: -
Summary of results
*: 6 values
An in vitro study was performed for the assessment of skin irritation on a reconstructed human epidermis (RhE; epiCS®). The experiment was carried out in accordance to OECD TG 439 with the neat substance. 30 mg of the test item was applied topically on the RhE, plus 30 µL saline to moisten and ensure good contact with the tissue surface. After an exposure period of 20 minutes (room temperature) and a post-exposure incubation of 42 hours (37 °C, 5 % CO2, maximum humidity), the cell viability was 91.8 %, as measured by a MTT conversion assay. The test item was thus not considered to have an irritant potential to the skin.
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