Registration Dossier

Environmental fate & pathways

Adsorption / desorption

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
adsorption / desorption: screening
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance has a low octanol water partition coefficient and the adsorption potential of this substance is related to this parameter
Endpoint:
adsorption / desorption
Remarks:
adsorption
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2009
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Two QSAR estimations are performed. One is described in the EU Technical Guidance Document, the other is used by the UDS EPA.
Principles of method if other than guideline:
QSAR estimation by 2 methods.
GLP compliance:
no
Type of method:
other: QSAR
Radiolabelling:
no
Test temperature:
Not relevant.
Analytical monitoring:
not required
Details on sampling:
Not relevant.
Details on matrix:
Not relevant.
Details on test conditions:
Not relevant.
Computational methods:
Adsorption coefficient per organic carbon (Koc):

1) Using the equation provided in the ECB Technical Guidance Document of 2000 for triazines: logKoc = 0.30 logKow + 1.5 and logKow = -1.22.
Result: logKoc = 1.13.

2) Using the programme KOCWIN v2.00:
Result based on molecular connectivity index: logKoc = 1.51.
(Result based on a calculated logKow of -1.37: logKoc = 0.0002.)
Type:
log Koc
Value:
1.13

Adsorption coefficient per organic carbon (Koc):

1) Using the equation provided in the ECB Technical Guidance Document of 2000 for triazines:

logKoc = 0.30 logKow + 1.5 and logKow = -1.22: -> logKoc = 1.13.

2) Using the programme KOCWIN v2.00:

Based on molecular connectivity index: logKoc = 1.51.

(Based on a calculated logKow of -1.37: logKoc = 0.0002.)

Conclusions:
Melamine has an estimated low ability to adsorb to soil.
Executive summary:

Adsorption coefficient per organic carbon (Koc):

1) Using the equation provided in the ECB Technical Guidance Document of 2000 for triazines: logKoc = 0.30 logKow + 1.5 and logKow = -1.22

Result: logKoc = 1.13.

2) Using the programme KOCWIN v2.00:

Result: logKoc = 1.51.

Endpoint:
adsorption / desorption: screening
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Justification for type of information:
Please refer to the analogue justification attached to section 13
Reason / purpose:
read-across source
Type:
log Koc
Value:
1.13 dimensionless
Remarks on result:
other: Source, Supporting, RA-A, CAS 108-78-1, QSAR.

Description of key information

Key value for chemical safety assessment

Additional information

Experimental data on the transport of diphosphoric acid, compound with 1,3,5-triamine (1:2) are not available. Based on the experimentally determined low log Pow of the substance (log Pow -1.24 at 20 °C, OECD 107) a low adsorption potential of the substance is expected.