Sodium salts of [[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid (1-3 Na:1)

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

secondary literature

Principles of method if other than guideline:

No details are available on the guideline used to determine this result.

GLP compliance:

not specified

Type of method:

other: No data

Key result

Water solubility:

>= 520 other: g/kg

Temp.:

25 °C

Remarks on result:

other: the source reports the solubility as "completely miscible"

Conclusions:

DTPMP-H was reported as miscible in water in secondary literature. The original reference was not available for review and no further information is available. The reliability of this result is not assignable.

Reference 2

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Principles of method if other than guideline:

no data

GLP compliance:

not specified

Type of method:

other: No data

Key result

Water solubility:

ca. 700 other: g/kg

Remarks on result:

other: Temperature and pH not stated

Phosphonate salts are highly water soluble and some are formulated as aqueous. Solutions containing up to 70 % active material. Free acids are less soluble than the salts; however, aqueous solutions in excess of l % active material can be prepared.

An infinite water solubility value was reported in the handbook which represents the water solubility is greater than >1 *10E+6 (the substance is miscible in water).

Conclusions:

DTPMP-H was reported as miscible in water in a handbook which has been subject to peer-review and in which the original data sources are traceable. The result is considered to be reliable.

Description of key information

Water solubility [DTPMP (1-3Na)]: The substance is very soluble in water and has water solubility values of ≥500 g/L at ambient conditions based on weight of evidence

Key value for chemical safety assessment

Water solubility:

500 g/L

at the temperature of:

25 °C

Additional information

The substance DTPMP (1-3Na) (and its analogues) are known to be highly hydrophilic and extremely water-soluble. Although suppliers' literature is much less detailed than laboratory study reports, given the range of values expected for these types of substance, the uncertainty is not significant in respect of environmental exposure or human health exposure modelling. Typical concentrations of aqueous solutions in commercial supply provides weight of evidence of high loadings of approximately 50%.

 

DTPMP-H was reported as miscible in water in a handbook (Gledhill 1992) which has been subject to peer-review and in which the original data sources are traceable. The result is considered to be reliable. Many commercial solutions at approx.500 g/L are reported in company literature. The original references were not available for review and no further information is available. The reliability of those results is not assignable.

 

Phosphonate salts are highly water soluble and are supplied as aqueous solutions. Free acids are less soluble than the salts; however, aqueous solutions in excess of l% active material can be prepared. The aqueous solution of sodium and potassium salts are miscible in water. DTPMP-2Na is reported as miscible with water.