Orthoperiodic acid

Oxidising properties

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1 August 2012 to 23 August 2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

other: read-across target

Qualifier:

according to guideline

Guideline:

EU Method A.17 (Oxidising Properties (Solids))

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Contact with:

powdered cellulose

Key result

Sample tested:

other: 2:1 test material to cellulose

Parameter:

preliminary test

Remarks on result:

vigorous reaction in the preliminary test

Remarks:

The cone immediately ignited and flared with a bright orange flame. The cone fully combusted within 2 seconds leaving a black fluffy residue.

Interpretation of results:

other: Classified as an oxidiser in accordance with EU criteria

Conclusions:

The test material was determined to have oxidising properties.

Executive summary:

The oxidising properties of the test material were investigated in a GLP study which was conducted in accordance with the standardised guideline EU Method A.17. Powdered test material and cellulose were mixed in a 2:1 ratio and formed into a cone (approximately 3.5 cm diameter at the base and 2.5 cm high) on a non-porous, non-combustible board. The cone was ignited with an air-rich Bunsen burner flame and the mode, vigour and duration of the reaction recorded.

The cone immediately ignited and flared with a bright orange flame. The cone fully combusted within 2 seconds leaving a black fluffy residue. The test material was determined to have oxidising properties.

Reference 2

Endpoint:

oxidising solids

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Justification for type of information:

Read-across to structurally similar substance sodium periodate (CAS 7790-28-5). Sodium periodate is the sodium salt of periodic acid.

Reason / purpose for cross-reference:

read-across source

Key result

Sample tested:

other: 2:1 test material to cellulose

Parameter:

preliminary test

Remarks on result:

vigorous reaction in the preliminary test

Remarks:

The cone immediately ignited and flared with a bright orange flame. The cone fully combusted within 2 seconds leaving a black fluffy residue.

Reference 3

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

16 March 2018 to 11 December 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.17 (Oxidising Properties (Solids))

Version / remarks:

2016

Deviations:

no

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test O.1 (Test for oxidizing solids)

Version / remarks:

2015

Deviations:

no

GLP compliance:

yes

Contact with:

other: Potassium bromate and cellulose in a 3:7, 2:3 and 3:2 (w/w) ratio.

Duration of test (contact time):

3 min

Sample tested:

reference: 3:2 mixture potassium bromate + cellulose

Parameter:

mean burning time

Result:

21 s

The mean burning time of the 4:1 test item mixture was less than the mean burning time of the 3:2 (w/w) reference mixture. According to this, the test item has oxidising properties and is to be classified as Division 5.1 in packing group I.

Burning Rates of Potassium Bromate / Cellulose Mixtures

Potassium bromate/cellulose (w/w)	Burning time (s)	Mean burning time (s)
3:7	114	115
	121
	111
	110
	118
2:3	50	51
	54
	45
	55
	52
3:2	21	21
	19
	24
	19
	24

 

Burning Rates of Test Item / Cellulose Mixtures

Test item/cellulose (w/w)	Burning time [s]	Mean burning time [s]
1:1	- *	27
	21
	34
	25
	27
4:1	16	20
	25
	21
	19
	17

* Burning time mixture unknown, since spontaneous reaction with the heat of the plate was observed.

Conclusions:

Under the conditions of the test, the test material has oxidising properties and is classified as a Division 5.1 substance in packing group I.

Executive summary:

The oxidising properties of the test material were assessed according to EC Guideline A.17 and UN Test O.1 in accordance with the principles of GLP using reference mixtures of potassium bromate and cellulose in a 3:7, 2:3 and 3:2 (w/w) ratios.

The mean burning time of the 4:1 test material mixture was less than the mean burning time of the 3:2 (w/w) reference mixture. According to this, the test material has oxidising properties and is to be classified as Division 5.1 in packing group I.

Description of key information

Under the conditions of the test, the test material has oxidising properties and is classified as a Division 5.1 substance in packing group I.

Key value for chemical safety assessment

Oxidising properties:

yes

Additional information

Key Study: Lammers (2019)

The oxidising properties of the test material were assessed according to EC Guideline A.17 and UN Test O.1 in accordance with the principles of GLP using reference mixtures of potassium bromate and cellulose in a 3:7, 2:3 and 3:2 (w/w) ratios. The study was assigned a reliability score of 1 in accordance with the principles for assessing data quality as outlined by Klimisch et al. (1997).

The mean burning time of the 4:1 test material mixture was less than the mean burning time of the 3:2 (w/w) reference mixture. According to this, the test material has oxidising properties and is to be classified as Division 5.1 in packing group I.

Supporting Study:

The oxidising properties of the read across substance, sodium periodate, were investigated in a GLP study which was conducted in accordance with the standardised guideline EU Method A.17. The study was assigned a reliability score of 1 in accordance with the principles for assessing data quality as outlined by Klimisch et al (1997), however, since the data is available on a read across substance an overall reliability score of 2 is considered appropriate. Sodium periodate is considered to be a suitable substance for read across since it is the sodium salt of periodic acid.

During the study, powdered test material and cellulose were mixed in a 2:1 ratio and formed into a cone (approximately 3.5 cm diameter at the base and 2.5 cm high) on a non-porous, non-combustible board. The cone was ignited with an air-rich Bunsen burner flame and the mode, vigour and duration of the reaction recorded.

The cone immediately ignited and flared with a bright orange flame. The cone fully combusted within 2 seconds leaving a black fluffy residue. The test material was determined to have oxidising properties.

Justification for classification or non-classification

In accordance with the criteria for classification as defined in Annex I, Regulation (EC) No. 1272/2008, the test material requires classification for oxidising properties as Category 1 (H271; May cause fire or explosion, strong oxidiser).