Registration Dossier

Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Remarks:
Study meets generally accepted scientific principles, acceptable for assessment as supporting data

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Principles of method if other than guideline:
pH-measurements (10g/l) taken in the laboratory for solutions of pure, HMDTMP with increasing stoichometric amounts of the corresponding base (NaOH).
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
[[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid
EC Number:
239-931-4
EC Name:
[[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid
Cas Number:
15827-60-8
Molecular formula:
C9H28N3O15P5
IUPAC Name:
[(bis{2-[bis(phosphonomethyl)amino]ethyl}amino)methyl]phosphonic acid

Results and discussion

pH valueopen allclose all
pH value:
2.2
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP
pH value:
2.4
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-1
pH value:
2.7
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-2
pH value:
3.6
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-3
pH value:
4.9
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-4
pH value:
5.9
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-5
pH value:
6.9
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-6
pH value:
8.1
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-7
pH value:
10
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-8
pH value:
11
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-9
pH value:
11.3
Temp.:
20 °C
Concentration:
10 g/L
Remarks on result:
other: Stoichiometric loading of base equivalent to DTPMP-10

Any other information on results incl. tables

Table 1: Titration in water

Determination 1

Sample mass (mg) 171.9

Equivalent NaOH

0

1

2

3

4

5

6

7

8

 9  10

1N NaOH (ml)

0.000

0.287

0.574

0.861

1.147

1.434

1.721

2.008

2.295

 2.582  2.869

pH

2.29

2.49

2.83

4.04

5.59

6.69

7.72

9.06

10.51

 11.18  11.42

 

Determination 2

Sample mass (mg) 170.9

Equivalent NaOH

0

1

2

3

4

5

6

7

8

 9  10

1N NaOH (ml)

0.000

0.285

0.570

0.856

1.141

1.426

1.711

1.996

2.282

 2.567  2.852

pH

2.27

2.46

2.80

4.01

5.55

6.65

7.76

8.99

10.43

 11.12  11.35

Average

2.28

2.48

2.82

4.02

5.57

6.67

7.74

9.03

10.47

 11.15  11.38

 

 

Table 2: Titration in 0.2 M KCl

Determination 1

Sample mass (mg) 172.0

 

 

Equivalent NaOH

0

1

2

3

4

5

6

7

8

 9  10

1N NaOH (ml)

0.000

0.287

0.574

0.861

1.148

1.435

1.722

2.009

2.296

2.583   2.870

pH

2.22

2.41

2.72

3.57

4.86

5.90

6.89

8.16

10.07

 10.96  11.24

 

Determination 2

Sample mass (mg) 172.4              

Equivalent NaOH

0

1

2

3

4

5

6

7

 

 9  10

1N NaOH (ml)

0.000

0.288

0.575

0.863

1.151

1.439

1.726

2.014

2.302

 2.589  2.877

pH

2.25

2.44

2.75

3.57

4.87

5.91

6.88

8.13

10.02

 10.99  11.25

Average

2.24

2.42

2.74

3.57

4.86

5.90

6.88

8.14

10.04

 10.98  11.26

 

 

Applicant's summary and conclusion

Conclusions:
The pH of the substance has been determined using an acceptable scientific method. The result is considered reliable.