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Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 23, 2021
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Justification for type of information:
Alternative method most appropriate for this substance.
Principles of method if other than guideline:
OECD Guideline 104 (OECD Guidelines for the Testing of Chemicals) states vapor pressure may be calculated if the vapor pressure is expected to be less than 10 Pa. A different calculation method than the one detailed in Guideline 104’s Appendix, however, was deemed more appropriate for this sample type.
GLS Test Code 15118, Thermogravimetric analysis differential thermal analysis (TGA-DTA) Vapor Pressure, was used to determine the vapor pressure at 20 ºC of test material EC 701-251-5.
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
other: Thermogravimetric analysis differential thermal analysis
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
ca. 0.032 Pa
Remarks on result:
not measured/tested
Conclusions:
The vapor pressure of the substance EC 701-251-5 was evaluated using a modified method most appropriate for the large molecular weight, highly viscous, substance that has a very low vapor pressure that cannot be measured by traditional means.
The vapor pressure in this study was 0.0315 Pa @20C
Executive summary:

The vapor pressure of the substance EC 701-251-5 was evaluated using a modified method most appropriate for the large molecular weight, highly viscous, substance that has a very low vapor pressure that cannot be measured by traditional means.

The vapor pressure in this study was 0.0315 Pa @20C

Description of key information

The vapor pressure was evaluated using a modified method most appropriate for the large molecular weight, highly viscous, substance that has a very low vapor pressure that cannot be measured by traditional means.

The vapor pressure in this study was estimated as 0.0315 Pa @20 °C.

Key value for chemical safety assessment

Vapour pressure:
0.032 Pa
at the temperature of:
20 °C

Additional information

Vapor pressure was determined using an alternative method most appropriate for this type of material. The estimated value is 0,0315 Pa at 20 °C. In addition, a supporting study (Cheng, 2014) looked at the headspace vapor of EC 701 -251 -5 after the material was kept at 70 °C for 3 days. Neither the alkyl phenate sulfide substance or impurity (TPP; EC 310 -154 -3) was detected, further demonstrating that the vapor pressure is very low and inhalation exposure is expected to be low.