Registration Dossier
Registration Dossier
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EC number: 219-536-3 | CAS number: 2457-02-5
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 1.39 mg/m³
- Route of original study:
- Oral
DNEL related information
- Dose descriptor starting point:
- other: Derivation of the inhalation DNELs for strontium bis(2-ethylhexanoate) is based on the point of departure for the most sensitive endpoint for each individual constituent (strontium and 2-ethylhexanoic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 0.41 mg/kg bw/day
DNEL related information
- Dose descriptor starting point:
- other: Derivation of the dermal DNELs for strontium bis(2-ethylhexanoate) is based on the point of departure for the most sensitive endpoint for each individual constituent (strontium and 2-ethylhexanoic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- low hazard (no threshold derived)
Acute/short term exposure
- Hazard assessment conclusion:
- low hazard (no threshold derived)
Workers - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- medium hazard (no threshold derived)
Additional information - workers
In order to evaluate toxicological properties of the substance strontium bis (2 -ethylhexanoate), information on the assessment entities strontium cation and 2 -ethylhexanoate anion were considered. For a documentation and justification of that approach, please refer to the separate document attached to section 13, namely Read Across Assessment Report for strontium bis (2 -ethylhexanoate).
General Population - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 0.34 mg/m³
- Route of original study:
- Oral
DNEL related information
- DNEL derivation method:
- ECHA REACH Guidance
- Dose descriptor starting point:
- other: Derivation of the inhalation DNELs for strontium bis(2-ethylhexanoate) is based on the point of departure for the most sensitive endpoint for each individual constituent (strontium and 2-ethylhexanoic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 0.21 mg/kg bw/day
DNEL related information
- Dose descriptor starting point:
- other: Derivation of the dermal DNELs for strontium bis(2-ethylhexanoate) is based on the point of departure for the most sensitive endpoint for each individual constituent (strontium and 2-ethylhexanoic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- low hazard (no threshold derived)
Acute/short term exposure
- Hazard assessment conclusion:
- low hazard (no threshold derived)
General Population - Hazard via oral route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 0.16 mg/kg bw/day
DNEL related information
- Dose descriptor starting point:
- other: Derivation of the oral DNELs for strontium bis(2-ethylhexanoate) is based on the point of departure for the most sensitive endpoint for each individual constituent (strontium and 2-ethylhexanoic acid).
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- medium hazard (no threshold derived)
Additional information - General Population
In order to evaluate toxicological properties of the substance strontium bis (2 -ethylhexanoate), information on the assessment entities strontium cation and 2 -ethylhexanoate anion were considered. For a documentation and justification of that approach, please refer to the separate document attached to section 13, namely Read Across Assessment Report for strontium bis (2 -ethylhexanoate).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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