Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
96 h EC50 = > 120 mg/L, NOEC = 120 mg/L; Selenastrum capricornutum; EPA OTS 797.1050; Hoberg (1993)
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 120 mg/L
Additional information
In the aquatic environment, boron is expected to be the active species of orthoboric acid, potassium salt. Boron is not considered toxic to algae as evidenced by numerous toxicity studies. Additionally, orthoboric acid, potassium salt was tested as manufactured (45% w/w in highly refined mineral oil) in the algae, Selenastrum capricornutum, in accordance with EPA OTS 797.1050. During the study, the algal culture was exposed to the test material at nominal concentrations of 120, 37, 11, 3.3 and 1.1 mg/L under static conditions; all tests were conducted using water soluble fractions. Under the conditions of the study, the 96 hour NOEC, based on a reduction on cell density, was determined to be 1.1 mg/L. The 96 hour EC50 value (and 95% confidence limits), were calculated to be 26 (7.5 - 95) mg/L. The 96 hour NOEC based on growth rate was determined to be 120 mg/L. Due to the lack of a well-defined concentration response for growth rate, the 72 – 96 hour ErC50 was empirically estimated to be >120 mg/L. The study was performed in line with GLP and an accepted standardised guideline with a high standard of reporting and assigned a reliability score of 1.
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