Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-293-4 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
In a key semi-static 96-hour acute rainbow trout (Oncorhynchus mykiss)test (OECD 203; KS=1),10 animals/dose were exposed to water accommodated fractions (WAFs) of Intermediate fuel oils 30-380 (CAS # 68476-33-5) at loading rates of 0, 2.0, 5.1, 13, 32, and 79 mg/L. The LL50 was 79 mg/L (EMBSI, 2008a).
Supporting PETROTOX (version 4.01) modelled values are available. The model predicted an acute LL50 to be 2.56 mg/L.
Key value for chemical safety assessment
Additional information
In a key semi-static 96-hour acute rainbow trout (Oncorhynchus mykiss)test (OECD 203; KS=1),10 animals/dose were exposed to water accommodated fractions (WAFs) of Intermediate fuel oils 30-380 (CAS # 68476-33-5) at loading rates of 0, 2.0, 5.1, 13, 32, and 79 mg/L. The LL50 was 79 mg/L (EMBSI, 2008a).
In six reliable supporting semi-static 96-hour acute rainbow trout (Oncorhynchus mykiss) studies using WAF methodology, the LL50 values of other heavy fuel oil samples ranged from >94 to >1000 mg/L (EMBSI, 2008b,c,d; Shell, 1997a,b).
Supporting PETROTOX (version 4.01) modelled values are available. PETROTOX combines a partitioning model (used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading) with the Target Lipid Model (used to calculate acute and chronic toxicity of non-polar narcotic chemicals). PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a petroleum substance and membrane-water partition coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
The model predicted an acute LL50 to be greater than 2.56 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
