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EC number: 701-293-4 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
In a key semi-static 96-hour acute rainbow trout (Oncorhynchus mykiss)test (OECD 203; KS=1),10 animals/dose were exposed to water accommodated fractions (WAFs) of Intermediate fuel oils 30-380 (CAS # 68476-33-5) at loading rates of 0, 2.0, 5.1, 13, 32, and 79 mg/L. The LL50 was 79 mg/L (EMBSI, 2008a).
Supporting PETROTOX (version 4.01) modelled values are available. The model predicted an acute LL50 to be 2.56 mg/L.
Key value for chemical safety assessment
Additional information
In a key semi-static 96-hour acute rainbow trout (Oncorhynchus mykiss)test (OECD 203; KS=1),10 animals/dose were exposed to water accommodated fractions (WAFs) of Intermediate fuel oils 30-380 (CAS # 68476-33-5) at loading rates of 0, 2.0, 5.1, 13, 32, and 79 mg/L. The LL50 was 79 mg/L (EMBSI, 2008a).
In six reliable supporting semi-static 96-hour acute rainbow trout (Oncorhynchus mykiss) studies using WAF methodology, the LL50 values of other heavy fuel oil samples ranged from >94 to >1000 mg/L (EMBSI, 2008b,c,d; Shell, 1997a,b).
Supporting PETROTOX (version 4.01) modelled values are available. PETROTOX combines a partitioning model (used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading) with the Target Lipid Model (used to calculate acute and chronic toxicity of non-polar narcotic chemicals). PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a petroleum substance and membrane-water partition coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
The model predicted an acute LL50 to be greater than 2.56 mg/L.
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