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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

No toxicity studies have been carried out on microorganisms with registration substance. PETROTOX model v 4.01 predicted an LL50 of >1,000 mg/L and a EL10 of 0.95 mg/L.


QSAR predictions on toxicity to microorganisms of HFO have also been provided to support the read-across from HFO to registration substance.

Key value for chemical safety assessment

Additional information

The aquatic toxicity was estimated using the PETROTOX computer model, which combines a partitioning model (used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading) with the Target Lipid Model (used to calculate acute and chronic toxicity of non-polar narcotic chemicals). PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a petroleum substance and membrane-water partition coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.

The model predicted an LL50 of >1,000 mg/L and a EL10 of 0.95 mg/L.