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EC number: 254-754-2 | CAS number: 40027-38-1
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
In contrary to the aquatic tests where results of the available acute toxicity tests of N-(Oleyl alkyl)- 1,3 -propanediamine mono-oleates and one with N-(Oleyl alkyl)- 1,3 -propanediamine di-oleates are not comparable because the test solutions were prepared differently (bulk approach applied to the di-oleates), results from terrestrial and benthic tests should be comparable and should allow read across. In soil and sediment both mono- and di-oleates are expected to dissociate completely because through sorption of the cationic groups the dissociation equilibrium will lean to the side of full dissociation and results from diamines, mono and di-oleates should be identical when corrected for difference in molecular weight (MW).
For both the diamines and N-(Oleyl alkyl)- 1,3 -propanediamine di-oleates long term earthworm tests were performed according toOECD guideline 222 test with Eisenia fetida under GLP (reliabilty 1).
In both tests a56d-NOEC (reproduction, mortality and body weight) of 1000 mg/kg dry weight was observed. Because the mono-oleate has its MW in between that of the diamine and diamine di-oleate this result is used without correction for it MW difference.
Key value for chemical safety assessment
Additional information
According to Annex IX, 9.4.1 to the Reach Regulation short-term toxicity testing with terrestrial invertebrates does not need to be conducted as long-term toxicity data for terrestrial organisms is available (see 6.3.1).
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