Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

The substance was sensitizing in a valid LLNA assay, with moderate potential (EC3 = concentration of 5.79%).

There is evidence of cross-reactivity (cross sensitization upon repeated contact with different compounds) between CrIII and CrVI compounds (CrVI like in barium chromate, component at 15% in the registered substance).

Secondary source data: review:

Cross HJ, Faux SP, Sadhra S et al. Criteria Document for Hexavalent Chromium. International Chromium Development Association. April 1997.

Migrated from Short description of key information:

The substance was sensitizing in a LLNA assay.

Respiratory sensitisation

Endpoint conclusion
Additional information:

The substance does not include any of the chemical groups suspected to be related to respiratory sensitisation based on Guidance R7a, Table R.7.3-1.

Migrated from Short description of key information:

no data - not required

Justification for classification or non-classification

Skin: the substance was sensitizing in a LLNA assay and must therefore be classified as a sensitizer.

Respiratory: no data, not classified.

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