Registration Dossier
Registration Dossier
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EC number: 608-174-5 | CAS number: 28183-82-6
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Guideline study conducted in 2018
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- GLP compliance:
- no
- Dissociating properties:
- yes
- No.:
- #1
- pKa:
- 2.26
- Temp.:
- 23.5 °C
- No.:
- #2
- pKa:
- 8.23
- Temp.:
- 23.5 °C
- Conclusions:
- Two dissociation points identified and consistent with the free amine
It should be noted that the conclusions in the test report are based on incorrect details of chemical identity; at the time of testing the correct identity was still unknown.
Reference
Description of key information
Two pKa values were noted, consistent with the amine content.
Key value for chemical safety assessment
Additional information
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