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Ecotoxicological information

Short-term toxicity to fish

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
96 hours
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Justification for type of information:
Guidelines study from 2003 to GLP, but data not fully reported and no analytical confirmation
The results are considered valid in view of the methods used and in consideration of the known stability of the substance in water.
The substance is soluble in water and is supplied in water.
Qualifier:
according to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
yes (incl. QA statement)
Specific details on test material used for the study:
Commercial grade materials used with approximately 50% actives in water.
Results reported as commercial grade.
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
other: Scophthalmus maximus (turbot)
Details on test organisms:
No further details
Test type:
flow-through
Water media type:
saltwater
Limit test:
no
Total exposure duration:
96 h
Test temperature:
Temperature 13.5 - 16.5
pH:
7.95 - 9.64
Dissolved oxygen:
> 60% saturation
Salinity:
33% salinity; synthetic seawater used
Nominal and measured concentrations:
Range 0, 100, 300, 1000, 3000 mg/l expressed as 50% commercial grade materials (0 - 1500 mg/l actives)
Reference substance (positive control):
yes
Remarks:
3,5-dichlorophenol
Duration:
96 h
Dose descriptor:
LC0
Effect conc.:
> 300 - < 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
50% actives
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
ca. 550 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
50% actives
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
ca. 225 mg/L
Nominal / measured:
nominal
Conc. based on:
act. ingr.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
> 300 - < 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Remarks:
50% actives
Basis for effect:
mortality (fish)
Validity criteria fulfilled:
not specified
Conclusions:
Irrespective of limited reporting and absence of analysis, it is clear that the toxicity to fish is sufficiently low that classification does not apply.
High concentrations were toxic.

Description of key information

Figure cited is estimated for the active ingredient based on use of test material with ca 50% actives

Key value for chemical safety assessment

Marine water fish

Marine water fish
Effect concentration:
225 mg/L

Additional information