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Ecotoxicological information

Short-term toxicity to fish

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
10-1997
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study done under GLP and complete
Qualifier:
according to
Guideline:
other: OECD 203, EU method C1 of 92/69/EEC
GLP compliance:
yes
Analytical monitoring:
yes
Vehicle:
yes
Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: Acetone
Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)
Test type:
semi-static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h
Hardness:
CA 100 mg CaCO3/L
Test temperature:
13-14 C
pH:
7.4-7.5
Dissolved oxygen:
8.0-9.2 mg/L
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
> 1.4 mg/L
Basis for effect:
mortality
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
> 1.4 mg/L
Basis for effect:
mortality
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
> 1.4 mg/L
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 1.4 mg/L
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
> 1.4 mg/L
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
>= 1.4 mg/L
Details on results:
%Concentration loss over test: 56 ... 65
Validity criteria fulfilled:
yes
Conclusions:
Under the conditions of the test, the LC50 >1.4 mg/L (greater than the maximum water solubility)

Description of key information

One OECD 203 GLP study is available.  The EC50 is greater than the maximum water solubility, thus it is not acutely toxic to fish.

Key value for chemical safety assessment

Additional information