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Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation: in vitro / ex vivo
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is a strong acid (pH ≤ 2.0) or base (pH ≥ 11.5) and the available information indicates that it should be classified as skin corrosion (Category 1, 1A, 1B or 1C)
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
no guideline followed
Principles of method if other than guideline:
Internal company data provided a pH value measured using a standard pH meter.
GLP compliance:
no
pH value:
1
Temp.:
20 °C
Remarks on result:
other: Temperature assumed. Concentration unknown.
Conclusions:
The pH of the test substance was determined to be 1 using a standard pH meter.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion

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