Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

The absorption efficiencies used in the assessment are:
Dermal - 10%
Oral - 100%
Inhalation - 100%

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential
Absorption rate - oral (%):
Absorption rate - dermal (%):
Absorption rate - inhalation (%):

Additional information

There are no specific toxicokinetic studies of 2 -EHDPP, but toxicology testing appears to indicate that it is readily absorbed via the oral route. Due to its rapid hydrolysis in water, it may be appropriate to consider the toxicokinetics of phenol for oral and inhalation routes since there would be a high likelihood of hydrolysis via these routes. The Phenol RAR (ECB 2006) concludes 100% absorption via the oral and inhalation routes and rapid elimination with low potential for bioaccumulation. These conclusions are also being applied to 2 -EHDPP.

The basis for the dermal absorption recommendation is discussed in Section 7.1.2.