Registration Dossier
Registration Dossier
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EC number: 949-892-1 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Remarks:
- VEGA QSAR Daphnia Magna LC50 48h DEMETRA 1.0.4.
- Adequacy of study:
- key study
- Study period:
- 2019
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model, but not (completely) falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- VEGA QSAR Daphnia Magna LC50 48h DEMETRA 1.0.4.
Data source
Reference
- Reference Type:
- other: QSAR DATA
- Title:
- Daphnia acute toxicity key laurates
- Author:
- VEGA
- Year:
- 2 019
- Bibliographic source:
- VEGA QSAR Daphnia Magna LC50 48h DEMETRA 1.0.4.
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- VEGA QSAR Daphnia Magna LC50 48h DEMETRA 1.0.4.
Test material
- Reference substance name:
- Esterification products of alcohols C12-13 linear and branched with lauric acid
- EC Number:
- 949-892-1
- IUPAC Name:
- Esterification products of alcohols C12-13 linear and branched with lauric acid
- Test material form:
- liquid
Constituent 1
Test organisms
- Test organisms (species):
- Daphnia magna
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0.042 mg/L
- Remarks on result:
- not measured/tested
- Remarks:
- no effect up to the limit of the substance water solubility was observed in Octyl laurate (QSAR elaboration)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0.031 mg/L
- Remarks on result:
- not measured/tested
- Remarks:
- no effect up to the limit of the substance water solubility was observed in Nonyl laurate (QSAR elaboration)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0.023 mg/L
- Remarks on result:
- not measured/tested
- Remarks:
- no effect up to the limit of the substance water solubility was observed in Decyl laurate (QSAR elaboration)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0.021 mg/L
- Remarks on result:
- not measured/tested
- Remarks:
- no effect up to the limit of the substance water solubility was observed in Isodecyl laurate (QSAR elaboration)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0.018 mg/L
- Remarks on result:
- not measured/tested
- Remarks:
- no effect up to the limit of the substance water solubility was observed in Undecyl laurate (QSAR elaboration)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0.014 mg/L
- Remarks on result:
- not measured/tested
- Remarks:
- no effect up to the limit of the substance water solubility was observed in Dodecyl laurate (QSAR elaboration)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0.011 mg/L
- Remarks on result:
- not measured/tested
- Remarks:
- no effect up to the limit of the substance water solubility was observed in Tridecyl laurate (QSAR elaboration)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0.009 mg/L
- Remarks on result:
- not measured/tested
- Remarks:
- no effect up to the limit of the substance water solubility was observed in Isotridecyl laurate (QSAR elaboration)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0.009 mg/L
- Remarks on result:
- not measured/tested
- Remarks:
- no effect up to the limit of the substance water solubility was observed in Tetradecyl laurate (QSAR elaboration)
- Key result
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- ca. 0.007 mg/L
- Remarks on result:
- not measured/tested
- Remarks:
- no effect up to the limit of the substance water solubility was observed in Hexadecyl laurate (QSAR elaboration)
Applicant's summary and conclusion
- Conclusions:
- no effect up to the limit of the substance water solubility was observed.
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