Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 828-229-9 | CAS number: 7019-19-4
Endpoint summary
Administrative data
Description of key information
Acute (short-term) toxicity to aquatic invertebrates
The acute toxicity of 1 -hydroxyoctan-2 -one towards the aquatic invertebrate daphna magna was investigated in an OECD 202 guideline study conducted in accordance with GLP including TOC chemical analysis to confirm exposure concentrations (Klimish 1).
The acute 48h EC50 value for invertebrates (daphnia magna) exposed to 1-hydroxyoctan-2-one was determined to be 39.1 mg/L (nominal). As the measured test item concentrations are within ± 20 % of the nominal concentrations, according to OECD 202 (2004), all results are given in relation to the nominal test item concentrations.
Toxicity to aquatic algae and cyanobacteria
The toxicity of 1 -hydroxyoctan-2 -one towards the aquatic plant algae species raphidocelis supcapitata was investigated in an OECD 201 guideline study conducted in accordance with GLP including TOC chemical analysis to confirm exposure concentrations (Klimisch 1).
The 72h EC50 value for algae exposed to 1-hydroxyoctan-2-one was determined to be 105.1 mg/L and 45.53 mg/L based on growth rate and yield, respectively. 72h EC10 values were 39.3 and 17.6 mg/L for effects on growth rate and yield, respectively. The 72h NOEC based on growth rate was determined to be 12.5 mg/L. As the measured test item concentrations are within ± 20 % of the nominal concentrations, according to OECD 202 (2004), all results are given in relation to the nominal test item concentrations.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
