Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information


The hydrolytic stability of the test item, Reaction mass of disodium N,N'-[(2-hydroxy-5-nonylphen-1,3-ylene)bis(methylene)]bis[N-methylaminoacetate] and sodium N-[(2-hydroxy-5-nonylphenyl)methyl]-N-methylaminoacetate, was assessed at a GLP accredited laboratory according to the OECD Guideline 111, “Hydrolysis as a function of pH” (Fox, 2019).


Test systems consisted of buffer solutions at pH 4, 7 and 9 treated with test item at nominal concentrations of 50 mg/L. Test solutions were incubated in the dark at 50.0 ± 0.5°C for a period of 120 hours. Duplicate samples were taken for test item concentration analysis (via HPLC-UV) from test solutions at 0, 24 and 120 hour periods.


The estimated half-life and rate constant (in parentheses) of the test item at 50°C were 399 hours (1.74E-3 h-1) and 117 hours (5.93E-3 h-1) at pH 7 and 9, respectively. The test item was hydrolytically stable at pH 4, showing <10% hydrolysis after 5 days at 50°C (equivalent to a half-life >1 year at 25°C).

Additional information