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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 January 2018 - 24 March 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC estimation method
Media:
other: Test item was diluted with methanol

Test material

Constituent 1
Chemical structure
Reference substance name:
m-bis(2,3-epoxypropoxy)benzene
EC Number:
202-987-5
EC Name:
m-bis(2,3-epoxypropoxy)benzene
Cas Number:
101-90-6
Molecular formula:
C12H14O4
IUPAC Name:
2-({3-[(oxiran-2-yl)methoxy]phenoxy}methyl)oxirane
Test material form:
liquid: viscous
Details on test material:
Identification: m-bis(2,3-epoxypropoxy)benzene
EC Number: 202-987-5
Physical state/Appearance: colorless slightly viscous liquid
Batch: 53715080
Purity: not provided
Expiry Date: 05 Aug 2019
Storage Conditions: room temperature in the dark
Specific details on test material used for the study:
- Source and lot/batch No.of test material: 53715080
- Storage condition of test material: Room temperature in the dark
Radiolabelling:
no

Study design

Test temperature:
30 °C

HPLC method

Details on study design: HPLC method:
EQUIPMENT
HPLC System : Agilent Technologies 1200 Series
Detector type : variable wavelength (VW)
Column : HSS CYANO 5 μm (150 x 4.6 mm id)
Column temperature : 30 °C
Mobile phase : Methanol: purified water (55:45 v/v)
pH of mobile phase : 5.7
Flow-rate : 1.0 mL/min
Injection volume : 10 μL
VW detector wavelength : 210 nm (standards and dead time)
220 nm (sample)
- Method: The dead time was determined by measuring the retention time of formamide (purity* 99.6%, 607 mg/L solution in methanol: purified water 55:45 v/v) REPETITIONS
- Number of determinations: The sample, dead time and reference standard solutions were injected in duplicate
EVALUATION
- Calculation of capacity factors k': Equation 18 in report
- Calculation of retention times: log k' versus log Koc of the reference standards was plotted using linear regression
- Determination of the log Koc value: equation 19 in report

Batch equilibrium or other method

Analytical monitoring:
yes
Details on sampling:
- Concentrations: Test item (0.1022 g) was diluted to 100 mL with methanol to give a concentration of 1.02 g/L.

Results and discussion

Adsorption coefficient
Key result
Type:
log Koc
Value:
ca. 1.65 dimensionless
pH:
5.7
Temp.:
30 °C

Applicant's summary and conclusion

Validity criteria fulfilled:
not applicable
Conclusions:
The adsorption coefficient of the test item has been determined to be 45.1, log10 Koc 1.65. The result classified the test item as having very high mobility.