Registration Dossier
Registration Dossier
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EC number: 827-162-2 | CAS number: 2218502-12-4
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- See report in section 13 "Other reports"
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 3 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Duration:
- 3 h
- Dose descriptor:
- IC0
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
Reference
Description of key information
The toxicity to aquatic microorganisms is determined by read-across to the structural analogue substance Direct Black 168 Na salt (CAS 93281 -13 -1). The source and the target substance have the same structure in respect to the anionic constituents.
One test conducted according to OECD Guideline 209 on the structural analogue substance resulted on one IC50 >100 mg/L value.
Based on the IC value obtained and considering the existing information, the substance is not harmful to microorganisms, and the same results applicable to the target substance.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 101 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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