Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: internal guideline used, no GLP
Cross-reference
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1980
Report date:
1980

Materials and methods

Test guideline
Qualifier:
no guideline available
Deviations:
not applicable
Principles of method if other than guideline:
-
GLP compliance:
not specified
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
4-amino-2-methylpyrimidine-5-carbonitrile
EC Number:
211-814-2
EC Name:
4-amino-2-methylpyrimidine-5-carbonitrile
Cas Number:
698-29-3
Molecular formula:
C6H6N4
IUPAC Name:
4-amino-2-methylpyrimidine-5-carbonitrile

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
unchanged (no vehicle)
Doses:
no information
No. of animals per sex per dose:
5 or 10
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
620 mg/kg bw
Based on:
test mat.
Remarks:
after 24 hours
95% CL:
>= 515 - <= 725

Any other information on results incl. tables

-

Applicant's summary and conclusion

Conclusions:
-
Executive summary:

-