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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

The LD50 was greater than 2000 mg/kg bw in rats. Accordingly, the test item was considered to be in Acute Toxic Category 5 (unclassified).

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
discriminating dose
2 000 mg/kg bw

Additional information

At a single oral dose of 2000 mg/kg bw all animals survived. Abnormal physical signs included rigid muscle tone, abnormal gait, ataxia and soling/wetnees of anogenital area in day 1. Body weight changes were normal in 4/6 animals. One female lost weight between days 7 and 19. Another female lost weight between days 14 and 19. Necropsy results were normal.

Justification for classification or non-classification

The substance does not meet classification criteria under EU Directive 67/548/EEC for acute oral toxicity.

The substance does not meet classification criteria under Regulation (EC) No 1272/2008 for acute toxicity.