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Administrative data

Description of key information

The LD50 was greater than 2000 mg/kg bw in rats. Accordingly, the test item was considered to be in Acute Toxic Category 5 (unclassified).

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
discriminating dose
Value:
2 000 mg/kg bw

Additional information

At a single oral dose of 2000 mg/kg bw all animals survived. Abnormal physical signs included rigid muscle tone, abnormal gait, ataxia and soling/wetnees of anogenital area in day 1. Body weight changes were normal in 4/6 animals. One female lost weight between days 7 and 19. Another female lost weight between days 14 and 19. Necropsy results were normal.

Justification for classification or non-classification

The substance does not meet classification criteria under EU Directive 67/548/EEC for acute oral toxicity.

The substance does not meet classification criteria under Regulation (EC) No 1272/2008 for acute toxicity.