Registration Dossier
Registration Dossier
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EC number: 950-576-0 | CAS number: -
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
The log Koc value for the major component was determined to be 5.12 (Koc: 1.3E05).
Key value for chemical safety assessment
- Koc at 20 °C:
- 130 000
Additional information
The adsorption coefficient (Koc) of the substance was determined using the HPLC estimation method based on soil-adsorption reference data. The study was performed in accordance with EC C.19 and OECD 121 and in compliance with GLP. Formamide was used as unretained substance. For the construction of the regression line, eight references substances (with log Koc range according to OECD TG121: 1.26 to 5.63 at ca. 20°C) were used. Duplicate injections of unretained substance, reference substances and test item in an UPLC-TUV system. The mobile phase was 55/45 (v/v) methanol/water and the wavelength of detection was 210 nm. The stationary phase contained cyanopropyl chains chemically bonded to silica. Log Koc of the main peak (52% peak area) at neutral pH: 5.12, Koc: 1.3E05. The log Koc value for the 2 minor components was determined to be 4.95 and 5.00 (Koc value: 9.0E04 and 1.0E05, resp.).
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