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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
2009
Deviations:
no
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
1,1,2-trimethyl-3-(4-sulphonatobutyl)-1H-benz[e]indolium
EC Number:
263-961-7
EC Name:
1,1,2-trimethyl-3-(4-sulphonatobutyl)-1H-benz[e]indolium
Cas Number:
63149-24-6
Molecular formula:
C19H23NO3S
IUPAC Name:
1,1,2-trimethyl-3-(4-sulfobutyl)-1H-benzo[e]indol-3-ium

Results and discussion

Mass median aerodynamic diameter:
15.8 µm
Geometric standard deviation:
>= 1.722 - <= 1.771
Particle sizeopen allclose all
Percentile:
D10
Mean:
6.64 µm
St. dev.:
0.186
Percentile:
D50
Mean:
13.6 µm
St. dev.:
0.126
Percentile:
D90
Mean:
21.6 µm
St. dev.:
0.569
Percentile:
other: Volume Weighted Mean
Mean:
13.8 µm
St. dev.:
0.201
Percentile:
other: Mode
Mean:
14.8 µm
St. dev.:
0.137

Applicant's summary and conclusion

Conclusions:
The particle size distribution of the test item was determined by means of Laser Diffraction Analysis using the medium volume (wet) module (MVM).
The D50 of the test item was determined to be 13.6 µm, the D10 was 6.64 µm and the D90 was 21.6 µm. The MMAD of the test item was calculated to be 15.8 µm.