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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
(Q)SAR
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Justification for type of information:
See attached background material.
1. SOFTWARE
EPI Suite 4.1
Qualifier:
according to guideline
Guideline:
other: REACH guidance on information requirements and chemical safety assessment, chapter R.6: QSARs and grouping of chemicals, May 2008.
Principles of method if other than guideline:
QSAR estimation
GLP compliance:
no
Radiolabelling:
no
Vehicle:
no
Details on estimation of bioconcentration:
BASIS INFORMATION
- Measured/calculated log Pow: Calculated
- Results from toxicokinetic study: No
- Results from residue study: No
- Monitoring data: No

BASIS FOR CALCULATION OF BCF
- Estimation software: BCFBAF v3.01 (EPISuite 4.1)
- Result based on measured log Pow of: Not applicable
- Result based on calculated log Pow of: 3.45
Type:
BCF
Value:
87.76 L/kg
Basis:
whole body w.w.
Calculation basis:
steady state
Remarks on result:
other: QSAR estimate, regression-based, using EPISuite (BCFBAF v3.01)
Validity criteria fulfilled:
not applicable
Conclusions:
The bioconcentration factor (BCF) for (3E)-dec-3-en-2-one from the regression based method is 87.76 L/kg ww (estimated by Epi SuiteTMv 4.1BC/FBAF v3.01), indicating the substance should have a low bioconcentration potential in accordance with ECHA Guidance on information requirements and chemical safety assessment, Chapter R. 7a.
Executive summary:

The bioconcentration factor (BCF) for (3E)-dec-3-en-2-one from the regression based method is 87.76 L/kg ww (estimated by Epi SuiteTMv 4.1BC/FBAF v3.01), indicating the substance should have a low bioconcentration potential in accordance with ECHA Guidance on information requirements and chemical safety assessment, Chapter R. 7a.

Description of key information

The bioconcentration factor (BCF) for (3E)-dec-3-en-2-one from the regression based method is 87.76 L/kg ww (estimated by Epi SuiteTM v 4.1BC/FBAF v3.01), indicating the substance should have a low bioconcentration potential in accordance with ECHA Guidance on information requirements and chemical safety assessment, Chapter R. 7a.

Key value for chemical safety assessment

BCF (aquatic species):
87.76 L/kg ww

Additional information