Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Experimental studies are available for all trophic levels investigating the short- and long-term effects of the test substance on species of fish, aquatic invertebrates, and algae.


Short-term toxicity data are available for three trophic levels (aquatic invertebrates, fish and algae). The most sensitive species was the water flea Daphnia magna (OECD 202) with a 48h-EC50 value of 43 mg/L (mean measured). Two studies investigated the toxicity of the test substance on fish. One study was performed with the freshwater species Bluegill Lepomis macrochirus and five test concentrations and the second study was performed as a limit test with the saltwater species Cyprinodon variegatus. In both tests, no toxic effects of the test substance on fish were observed. Therefore, 96 h LC50 values for B. Lepomis and C. vairegatus were > 120 mg a.s./L (mean measured) and >129 mg a.s./L (mean measured), respectively.

In a 72-h study with green algae Pseudokirchneriella subcapitata (OECD 201), the derived EC50 value was > 120 mg a.s./L for cell density, area under the curve, and growth rate. NOEC and LOEC values were determined to be 7.4 mg a.s./L and 15 mg a.s./L (mean measured), respectively, for cell density and growth rate.

One long-term toxicity tests for fish is available. In the 90-day key study (OECD 210), freshly fertilized rainbow trout eggs were exposed to five test substance concentrations. Derived NOEC was 11 mg/L (mean measured). In the study investigating the toxicity to aquatic invertebrates (according to OECD 211) no effect on survival, reproduction or growth was detected in D. magna up to the highest test concentration of 6 mg/L (mean measured). Therefore, the NOEC was ≥ 6.0 mg a.s./L.

The key study on the toxicity to activated sludge microorganisms shows, that the substance does not significantly inhibit the respiration of activated sludge microorganisms (NOEC >= 100 mg/L).