Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental start date 14 September 2018, Experimental completion date 09 November 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
hot stages

Test material

1
Chemical structure
Reference substance name:
2-bromo-6-(4-methylbenzoyl)pyridine
EC Number:
618-079-0
Cas Number:
87848-95-1
Molecular formula:
C13H10BrNO
IUPAC Name:
2-bromo-6-(4-methylbenzoyl)pyridine

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
ca. 90 - ca. 99 °C
Atm. press.:
1 031 mBar

Any other information on results incl. tables

The results of duplicate melting point determinations on the test item were as follows:

Temperature (°C)
   Melting stage* Sample I Sample II
A 90.5 90
B 95 94.5
C 97 97
D 97.5 97.5
E 98.5 98.5

*as referenced in OECD Guideline 102.

Applicant's summary and conclusion

Conclusions:
2-Bromo-6-(4-toluoyl)pyridine was found to melt at temperatures between approximately 90 and 99°C.