Propionamide

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018-11-20 to 2019-01-10

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: Particle Size Distribution (CIPAC MT 59)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

sieving

Type of particle tested:

primary particle

Type of distribution:

mass based distribution

Key result

Percentile:

D50

Mean:

1 131 µm

St. dev.:

0

Percentile:

D10

Mean:

386 µm

St. dev.:

0

Percentile:

D90

Mean:

3 959 µm

St. dev.:

0

Particle Size Distribution

 

Results of the sieving analysis

Sieve size in µm	Residue on sieve in g	Mass %	Total %
16,000	2.1	0.93	100.00
11,200	6.8	3.01	99.07
8,000	4.0	1.77	96.05
5,600	9.2	4.08	94.28
4,000	13.6	6.03	90.20
2,800	26.5	11.75	84.18
2,000	30.6	13.56	72.43
1,400	29.7	13.16	58.87
1,000	28.5	12.63	45.70
710	35.3	15.65	33.07
500	21.3	9.44	17.42
355	10.5	4.65	7.98
250	4.9	2.17	3.32
180	1.5	0.66	1.15
125	0.7	0.31	0.49
90	0.3	0.13	0.18
< 90*	0.1	0.02	0.04

*bottom tray

 

The D10, D50, and D90 value was determine by applying a linear equation on the two points closest to the 10 %, 50 %, or 90 % mark on the cumulative distribution. The equation was solved for the corresponding value.

 

Results for D10, D50, and D90 value

D10:	386 µm
D50:	1131 µm
D90:	3959 µm

 

Conclusions:

The median particle size of the test item was determined by laser diffraction measurement to be D50 = 1131 µm.

Executive summary:

A study was conducted according to OECD TG 110 and CIPAC MT 59 in order to determine the particle size distribution of the test item. The particle size distribution was determined sieve analysis. The particle size distribution is determined using sieves with different mesh sizes. The sieves are stacked in order of aperture size with the largest at the top and the receiver pan at the bottom. The test item was filled into the sieve with the largest size. The tower was than shaken using a sifting machine for 5 minutes with an amplitude of 100 %. The residue on each sieve was then weighed. The D10, D50, and D90 value was determine by applying a linear equation on the two points closest to the 10 %, 50 %, or 90 % mark on the cumulative distribution. The median particle size D50 of test item was determined to be 1131 μm.

Description of key information

The median particle size of the test item was determined by laser diffraction measurement to be D50 = 1131 µm (reference 4.5-1).

Additional information

A study was conducted according to OECD TG 110 and CIPAC MT 59 in order to determine the particle size distribution of the test item. The particle size distribution was determined sieve analysis. The particle size distribution is determined using sieves with different mesh sizes. The sieves are stacked in order of aperture size with the largest at the top and the receiver pan at the bottom. The test item was filled into the sieve with the largest size. The tower was than shaken using a sifting machine for 5 minutes with an amplitude of 100 %. The residue on each sieve was then weighed. The D10, D50, and D90 value was determine by applying a linear equation on the two points closest to the 10 %, 50 %, or 90 % mark on the cumulative distribution. The median particle size D50 of test item was determined to be 1131 μm.