Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15.5.2019-29.5.2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 115 (Surface Tension of Aqueous Solutions)
Version / remarks:
27th July 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.5 (Surface Tension)
Version / remarks:
May 2008
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
ring method

Test material

Constituent 1
Chemical structure
Reference substance name:
Reference substance 001
Cas Number:
67-47-0
Molecular formula:
C6H6O3
impurity 1
Chemical structure
Reference substance name:
Fructose
EC Number:
200-333-3
EC Name:
Fructose
Cas Number:
57-48-7
Molecular formula:
C6H12O6
IUPAC Name:
D-fructose
impurity 2
Chemical structure
Reference substance name:
1-(furan-2-yl)-2-hydroxyethanone
Cas Number:
17678-19-2
Molecular formula:
C6H6O3
IUPAC Name:
1-(furan-2-yl)-2-hydroxyethanone
impurity 3
Reference substance name:
Water
EC Number:
231-791-2
EC Name:
Water
Cas Number:
7732-18-5
Molecular formula:
H2O
IUPAC Name:
water
impurity 4
Chemical structure
Reference substance name:
Sodium formate
EC Number:
205-488-0
EC Name:
Sodium formate
Cas Number:
141-53-7
Molecular formula:
CH2O2.Na
IUPAC Name:
sodium formate
impurity 5
Chemical structure
Reference substance name:
Sodium nitrate
EC Number:
231-554-3
EC Name:
Sodium nitrate
Cas Number:
7631-99-4
Molecular formula:
HNO3.Na
IUPAC Name:
sodium nitrate
impurity 6
Chemical structure
Reference substance name:
Glucose
EC Number:
200-075-1
EC Name:
Glucose
Cas Number:
50-99-7
Molecular formula:
C6H12O6
IUPAC Name:
D-glucose
impurity 7
Chemical structure
Reference substance name:
Sodium acetate
EC Number:
204-823-8
EC Name:
Sodium acetate
Cas Number:
127-09-3
Molecular formula:
C2H4O2.Na
IUPAC Name:
sodium acetate
impurity 8
Chemical structure
Reference substance name:
2-furaldehyde
EC Number:
202-627-7
EC Name:
2-furaldehyde
Cas Number:
98-01-1
Molecular formula:
C5H4O2
IUPAC Name:
2-furaldehyde
impurity 9
Chemical structure
Reference substance name:
Sodium 4-oxovalerate
EC Number:
243-378-4
EC Name:
Sodium 4-oxovalerate
Cas Number:
19856-23-6
Molecular formula:
C5H8O3.Na
IUPAC Name:
sodium 4-oxopentanoate
impurity 10
Chemical structure
Reference substance name:
Formaldehyde
EC Number:
200-001-8
EC Name:
Formaldehyde
Cas Number:
50-00-0
Molecular formula:
CH2O
IUPAC Name:
formaldehyde
Test material form:
solid: crystalline
Details on test material:
freeze-dried material
Batch: 1808A-RO-C-I1-FD-Chg#3
Appearance Crystal / brown
Storage: Refrigerator (2 - 8 °C)
Expiring date: 31 December 2019
Specific details on test material used for the study:
Storage Conditions: Dry, dark and cooled (2 °C to 8 °C)
Expiry Date: 2019-12-31

Results and discussion

Surface tension
Key result
Surface tension:
66.04 mN/m
Temp.:
20 °C
Conc.:
1.072 g/L

Any other information on results incl. tables

Measured surface tension values

Value No.

1stMeasurement

(3 min after preparing the
 solution)

s[mN/m]

2ndMeasurement

(22 min after preparing the solution)

s[mN/m]

1

64.74

67.47

2

64.71

67.44

3

64.69

67.41

4

64.66

67.39

5

64.64

67.36

6

64.61

67.35

Mean value of the

individual values

64.68 ± 0.05

67.40 ± 0.05

Total mean value

66.04 ± 1.36

The test item has a mean surface tension of 66.04 mN/m. According to regulation EC No. 440/2008 Part A Method A.5 substances showing a surface tension lower than 60 mN/m under the conditions of method A.5 should be regarded as being surface active materials.Thus, the test item is not to be regarded as surface active.

Applicant's summary and conclusion

Conclusions:
The surface tension at 20 °C of the test item 5-(Hydroxymethyl)furfural was determined to be 66.04 mN/m. Therefore, it is not to be regarded as surface active material.
Executive summary:

According toOECD Test Guideline 115 and Regulation EC No. 440/2008 Part A Method A.5. the surface tension at 20 °C of the test item5-(Hydroxymethyl)furfuralwas determined to be:  66.04 mN/m

According to RegulationEC No. 440/2008 Part A Method A.5. the test item is not to be regarded as surface active material.

Categories Display