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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
other: Databases of chemical substances (Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
no guideline followed
Version / remarks:
For the assessment of hazardous properties can be used relevant alternative methods (non – testing methods - read-across/chemical categories, chemistry considerations or(Q)SAR etc.).
If the outputs from the application of alternative methods are not sufficiently conclusive, will be used recommended test method. First, the methods of in vitro and then the in vivo methods.

Data could be usable, access to the study and resolution of property rights should be ensured.
Recommended test method according to Regulation 440/2008: C.2 Daphnia sp. acute immobilisation testmation (OECD TG 202)
Principles of method if other than guideline:
not specified
GLP compliance:
not specified
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Daphnia sp.
Test type:
not specified
Water media type:
not specified
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
<= 1 mg/L
Remarks on result:
other: not specified

Description of key information

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
1 mg/L

Additional information

For the assessment of hazardous properties can be used relevant alternative methods (non – testing methods - read-across/chemical categories, chemistry considerations or(Q)SAR etc.).

If the outputs from the application of alternative methods are not sufficiently conclusive, will be used recommended test method.  First, the methods of in vitro and then the in vivo methods.

Data could be usable, access to the study and resolution of property rights should be ensured.

Recommended test method according to Regulation 440/2008:

C.2 Daphnia sp. acute immobilisation testmation (OECD TG 202)