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EC number: 947-652-0 | CAS number: 943986-70-7
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28 Jan 2019 - 20 Feb 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 2016
- Deviations:
- no
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Version / remarks:
- 1998
- Deviations:
- no
- Principles of method if other than guideline:
- In a preliminary test the substance was found to be very well soluble so the main study was not performed.
- GLP compliance:
- yes
- Type of method:
- flask method
Test material
- Reference substance name:
- Reaction mass of (S)-2-[(R)-2-Oxo-4-propyl-1-pyrrolidinyl]butyramide and (S)-2-[(S)-2-Oxo-4-propyl-1-pyrrolidinyl]butyramide
- Cas Number:
- 943986-70-7
- Molecular formula:
- C11H20N2O2
- IUPAC Name:
- Reaction mass of (S)-2-[(R)-2-Oxo-4-propyl-1-pyrrolidinyl]butyramide and (S)-2-[(S)-2-Oxo-4-propyl-1-pyrrolidinyl]butyramide
- Test material form:
- solid
- Details on test material:
- - Appearance: Off-white solid
- Storage condition of test material: At room temperature protected from light
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- > 1 000 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 1 110
- Incubation duration:
- 1 h
- Temp.:
- 20.1 °C
- Remarks on result:
- completely miscible
- Details on results:
- After the stirring period, the test solution was clear and visually no undissolved test item was observed.
It was concluded that the water solubility of the test item at 20°C was > 1 x 10^3 g/L.
Applicant's summary and conclusion
- Conclusions:
- The water solubility of the substance at 20°C was determined to be > 1000 g/L (flask method).
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