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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

DEGME; EC0 (96hr) >1000mg/L (limit study)

TEGME Measured EC20 (72hr) >500mg/L (limit study)

QSAR: predicts toxicity decreases with increasing molecular weight

Key value for chemical safety assessment

EC10 or NOEC for freshwater algae:
1 000 mg/L

Additional information

Toxicity data is available for a monoconstituent substance that is considered a conservative surrogate for the components of this multi-constituent substance as a whole.  In a study that approximates to guideline, 2 -(2 -methoxyethoxy)ethanol (DEGME) did not inhibit biomass increase by a factor of 50% at concentrations up to the maximum tested of 1000mg/l. The data would support a conclusion of no effects at 1000mg/l.  This result is supported by information from the ECOSAR QSAR model, which predicts that the 96hr EC50 value for algae would be 6600mg/l with equivalent values for TetraEGME and PentaEGME (the main components of the multi-constituent substance) of 28 and 59g/L respectively. the value for DEGME can therefore be used as a very conservative surrogate to predict the algal toxicity of this substance.