Registration Dossier
Registration Dossier
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EC number: 701-310-5 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Diethyleneglycol, propoxylated showed no sensitizing potential in the modified Local Lymph Node Assay (IMDS) in female NMRI mice after dermal application of up to and including a 50 % concentration. Additionally, no indication for a non-specific (irritant) activation was detected. Therefore, the concentration of 50 % turned out to be the NOEL for the parameters investigated in this study with respect to skin sensitization.
Since both, core molecule (2,2`oxybisethanol) and structural analogue (2,2`oxybisethanol, propoxylated) are not sensitizing, it can reliably concluded that 2,2`oxybisethanol ethoxylated and propoxylated is not a skin sensitizer.
Migrated from Short description of key information:
Non sensitiser in a modified Local Lymph Node Assay.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
The LLNA result indicates that the substance does not meet the criterion for classification as a skin sensitiser.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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