Benzododecinium chloride

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From July 04, 2019 to July 12, 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

GLP compliance:

yes (incl. QA statement)

Type of method:

other: Differential scanning calorimetry and photo cell detection method

Key result

Boiling pt.:

162.7 °C

Atm. press.:

1 013 hPa

The thermograms of the DSC runs PN18048 and PN18050 are shown in Figure 1 and Figure 2 (Kindly refer the attached background material secrion of the IUCLID). In the temperature range of 30 - 60°C, an endothermic effect (melting) was observed. Between 140 - 240°C a second endothermic effect could be detected. An exothermic effect is detected in the temperature range of 240 - 290°C. During the heating phase a distinct endothermic effect was observed in the temperature range of 30 - 60°C, which can be assigned to the melting of the test substance. As the onset temperatures in both tests do not deviate by more than 0.5 K from their mean value of 45.21°C, this temperature can be used as melting point. The test substance has a melting point of 45.2°C at atmospheric pressure (1011.2 hPa). The test substance showed a second endothermic signal in the temperature range of 160 - 260°C, which could not be clearly assigned to the boiling of the test substance. Thus, the photo cell detection method was performed. The apparatus detected automatically a temperature of 162.2°C at atmospheric pressure (1000 hPa) as the boiling of the test substance. With correction for the standard pressure (1013 hPa), the boiling point was determined to be 162.7°C. Due to the fact that the BOCHI Apparatus detected the boiling temperature very clearly, this temperature is used as boiling point of the test substance.

Conclusions:

Under the study conditions, boiling point of the test substance was determined to be 162.7°C at 1013 hPa.

Executive summary:

A study was conducted to determine the boiling point of the test substance, using differential scanning calorimetry and photo cell detection method, according to the OECD Guideline 103 and EC Method A.2, in compliance with GLP. Under the study conditions, boiling point of the test substance was determined to be 162.7°C at 1013 hPa (Hartmann, 2019).

Description of key information

The boiling point of the test substance was determined using the photo cell detection method according to OECD Guideline 103 and EC Method A.2 (Hartmann, 2019).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

162.7 °C