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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Remarks:
Sample sent to Vanta Bioscience Limited, K2B, 11th Cross Street, SIPCOT Industrial Complex, Gummidipundi- 601 201, Tamil Nadu, India for analysis.
Type of information:
experimental study
Adequacy of study:
key study
Study period:
99 days
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(3β-hydroxyolean-12-en-28-oyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-Serine
EC Number:
921-112-4
Molecular formula:
C53H91N7O11
IUPAC Name:
N-(3β-hydroxyolean-12-en-28-oyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-Serine
Test material form:
solid: particulate/powder

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Water media type:
other: Natural water (Ground water)
Limit test:
yes
Total exposure duration:
48 h

Test conditions

Hardness:
200mg/L
pH:
7.7 and 7.9
Dissolved oxygen:
7.74 and 7.88mg/L
Conductivity:
0.24mS.cm-1

Results and discussion

Effect concentrations
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
>= 38.97 - <= 47.55 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
behaviour
Remarks on result:
other: No abnormal was behaviour

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The Acute immobilisation EC50 for N-(3β-hydroxyolean-12-en-28-oyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-Serine in Daphnia magna at 48hrs exposure period is 43.26mg/L. The Study is performed as per OECD Guideline for testing of Chemicals, Test Guidelines No. 202.