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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
16.08.2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
2009
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of particle tested:
agglomerate
Type of distribution:
volumetric distribution
Key result
Percentile:
D50
Mean:
4.5 µm
Remarks on result:
other: SD not determined.
Percentile:
D10
Mean:
1.1 µm
Remarks on result:
other: SD not determined.
Percentile:
D90
Mean:
16 µm
Remarks on result:
other: SD not determined.

The test item consisted of agglomerates with different size and shape. The formation of agglomerates may have influenced the measurement.

The particles were introduced to the analyser beam by the dry powder feeder by direct spraying through the measuremnt area. The powder was loosened by an integrated vibrator. The particles were dispersed and fed to the optical system by pressurized dry air (15. bar). After passing the analyser beam the sample was collected in a vacuum cleaner.

After adjusting the laser, measuring the background and adjusting the correct particle concentration (obscuration) the measurement was started. The control software automatically performed three measurements. The average of these three measurements was given as result. Two test series of three measurements each were performed. The measurement time was8s.

For each test series fractions (left axis of the ordinate) and the siftings (right axis of the ordinate) are presented in percent by volume as a function of the particle size. Median values were calculated from unrounded values.

 

The median particle size L50(D (v, 0.5): 50 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1sttest series: L50=4.8μm

2ndtest series: L50=4.2μm

The average of the median particle size L50was: L50=4.5μm

 

The particle size L10 (D (v, 0.1 ): 10 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1sttest series: L10=1.1μm

2ndtest series: L10=1.0μm

The average of the particle size L10was: L10=1.1μm

 

The particle size L90(D (v, 0.9): 90 % of particle volume or particle mass with lower particle diameter) deduced from these distributions were:

1sttest series: L90=18.5μm

2ndtest series: L90=13.3μm

The average of the particle size L90was: L90=16μm

 

The particle size distribution showed a polymodal distribution. A first maximum was observed at approx. 4 - 6 µm with a shoulder at approx. 0.4 µm. A second maximum was observed at approximately 200 µm.

Conclusions:
The median particle size L50 of the test item deduced from the particle size distributions was 4.5 µm.
Executive summary:

The determination of the particle size distribution by laser diffraction of the test item was performed according to the OECD Guideline 110 by laser diffraction. The median particle size L50 of the test item deduced from the particle size distributions was 4.5 µm.

Description of key information

The median particle size L50 of the test item deduced from the particle size distributions was 4.5 µm.

Additional information

The determination of the particle size distribution by laser diffraction of the test item was performed according to the OECD Guideline 110 by laser diffraction. The median particle size L50 of the test item deduced from the particle size distributions was 4.5 µm.