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Ecotoxicological information

Toxicity to microorganisms

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Reference
Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1992
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
Version / remarks:
1984
Principles of method if other than guideline:
N/A
GLP compliance:
not specified
Test organisms (species):
activated sludge
Limit test:
no
Total exposure duration:
30 min
pH:
7.0
Key result
Duration:
30 min
Dose descriptor:
EC50
Effect conc.:
2.3 mg/L
Conc. based on:
other: CN-
Validity criteria fulfilled:
not specified
Conclusions:
Based on an experimental ASRIT study performed according to the OECD 209 guideline, the substance exhibits an EC50 of 2.3 mg/L
Executive summary:

Based on an experimental ASRIT study performed according to the OECD 209 guideline, the substance exhibits an EC50 of 2.3 mg/L

Description of key information

Following a read-across approach based on an experimental study from an activated sludge respiration inhibition assay, conducted in accordance with the guideline OECD 209 on the source substance potassium cyanide (Strotmann, 1992), a 30-minutes EC50 of 2.3 mg CN-/L is considered for the registered substance.

Key value for chemical safety assessment

EC50 for microorganisms:
2.3 mg/L

Additional information