Reaction mass of sodium methyl sulphate and 1-methylpyrodomop-3-carboxylate

Endpoint summary

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records

Reference

Endpoint:

skin sensitisation: in vitro

Type of information:

(Q)SAR

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Qualifier:

no guideline required

Principles of method if other than guideline:

not required, see documentation QSAR

GLP compliance:

no

Key result

Run / experiment:

other: n.a.

Parameter:

other: QSAR

Value:

1

Vehicle controls validity:

not applicable

Negative controls validity:

not applicable

Positive controls validity:

not applicable

Remarks on result:

positive indication of skin sensitisation

Interpretation of results:

Category 1 (skin sensitising) based on GHS criteria

Conclusions:

positive prediction of skin sensitaiation of Sodium methyl sulfate by QSAR

Endpoint conclusion

Endpoint conclusion:

adverse effect observed (sensitising)