Registration Dossier

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001
Report date:
2001

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
Deviations:
no
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
Deviations:
no

Test material

Constituent 1
impurity 1
Test material form:
liquid
Radiolabelling:
no

Results and discussion

Total recovery of test substance (in %)open allclose all
% Recovery:
ca. 94
pH:
4
Temp.:
50 °C
Duration:
ca. 119.5 h
% Recovery:
ca. 46
pH:
7
Temp.:
50 °C
Duration:
ca. 72 h
% Recovery:
ca. 34
pH:
9
Temp.:
50 °C
Duration:
ca. 3.5 h
% Recovery:
ca. 42
pH:
7
Temp.:
60 °C
Duration:
ca. 25 h
% Recovery:
ca. 23
pH:
7
Temp.:
70 °C
Duration:
ca. 23 h
% Recovery:
ca. 45
pH:
9
Temp.:
35 °C
Duration:
ca. 9 h
Dissipation DT50 of parent compoundopen allclose all
Key result
pH:
4
Temp.:
25 °C
DT50:
> 1 yr
Type:
not specified
Remarks on result:
other:
Key result
pH:
7
Temp.:
25 °C
Hydrolysis rate constant:
ca. 0.001 h-1
DT50:
ca. 994 h
Type:
(pseudo-)first order (= half-life)
Remarks on result:
other:
Key result
pH:
9
Temp.:
25 °C
Hydrolysis rate constant:
ca. 0.038 h-1
DT50:
ca. 18.1 h
Type:
(pseudo-)first order (= half-life)
Remarks on result:
other:

Applicant's summary and conclusion

Validity criteria fulfilled:
yes