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Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

No antigen specific activation of the cells of the immune system via dermal route was determined after application of up to and including 50% Oxaphthalimid. No indication for a non-specific (irritating) activation was detected, too. Therefore, the study does neither point to a non-specific (irritating) nor to a specific immunostimulating (sensitising) potential of the test item.


Migrated from Short description of key information:
Skin Sensitisation, LLNA/IMDS (NMRI mice, GLP, OECD TG 429, 406 and EPA OPPTS 870.2600): no non-specific (irritating) or specific immunostimulating (sensitising) properties
[Bayer AG, Report No. PH-34457, 2006-05-19]

Justification for classification or non-classification

Based on the study results a classification according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (CLP) is not required.

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