Registration Dossier

Administrative data

Endpoint:
pH
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 122 (Determination of pH, Acidity and Alkalinity)
Version / remarks:
2013
Deviations:
no
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid

Reagents

Reagent:
water

Results and discussion

pH value
Key result
pH value:
2.22
Temp.:
20 °C
Concentration:
1 other: % w/v

Any other information on results incl. tables

Table 1: Results of pH value measurements

Determination

pH value

Overall mean pH

After 1 minute

After 2 minutes

After 10 minutes

1

2.21

2.21

Not required

2.22

2

2.23

2.23

Not required

Applicant's summary and conclusion

Conclusions:
The pH value of a 1% w/v aqueous solution of the substance was determined to be 2.22 at 20 °C.
Executive summary:

The pH value of the substance was studied under GLP in accordance with OECD TG 122, using a calibrated pH meter. Two test solutions at a nominal concentration of 1% w/v were prepared by diluting aliquots of test substance (1.0275 and 1.0100 g) to 100 mL of high purity water (with a specification of resistance of >15 MΩ and a typical TOC content of 20 ppb). Each sample was then transferred to a sample cup and allowed to settle for a period of 1 minute before the pH value was determined. A second reading was done after 2 minutes. As the difference between the two readings did not exceed 0.1 pH units, a third reading after 10 minutes was not required. The results of the measurements were 2.21 and 2.23, giving a mean pH value of 2.22 at a concentration of 1% w/v and a temperature of 20 °C.