Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 848-535-6 | CAS number: 2267262-12-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.012 mg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.122 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.001 mg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.066 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.006 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.006 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
The PNEC derivation was as follows justified:
PNEC freshwater sediment: 0.066 mg/kg dw
K_(susp-water) = 1.36
RHO_(susp) = 1150
Conversion factor (wwt -> dwt): 4.6
PNEC_freshwater sediment
= (K_(susp-water)/ RHO_(susp)) * PNEC_freshwater * 1000
= (1.36/1150) * 0.0122 * 1000
= 0.0144 mg/kg wwt
= 0.066 mg/kg dw
PNEC marinewater sediment: 0.0064 mg/kg dw
K_(susp-water) = 1.36
RHO_(susp) = 1150
Conversion factor (wwt -> dwt): 4.6
PNEC_marinewater sediment
= (K_(susp-water)/ RHO_(susp)) * PNEC_marinewater * 1000
= (1.36/1150) * 0.00122 * 1000
= 0.0014 mg/kg wwt
= 0.0064 mg/kg dw
PNECsoil: 0.0056 mg/kg dw
K_(soil-water) = 0.692
RHO_(soil) = 1700
Conversion factor (wwt -> dwt): 1.13
PNEC_soil
= (K_(soil-water)/ RHO_(soil)) * PNEC_freshwater * 1000
= (0.692/1700) * 0.0122 * 1000
= 0.0049 mg/kg wwt
= 0.0056 mg/kg dw
Conclusion on classification
Classification related key information
- Biodegradation: not readily biodegradable: 8.8% degradation (O2 consumption) after 28 days (OECD TG 301D)
- Bioaccumulation: log Pow = 0.26 at 25 °C (calculated)
Aquatic acute toxicity
- Aquatic invertebrates: EC50 (48 h) > 100 mg/L (nominal, Daphnia magna, OECD 202)
- Algae: ErC50 (72 h) = 34.9 mg/L (measured geometric mean, Raphidocelis subcapitata, OECD 201)
- Fish: LC50 (96 h) > 100 mg/L (nominal, Danio rerio, OECD 203)
Aquatic chronic toxicity
- Algae: ErC10 (72 h) = 12.2 mg/L (measured geometric mean, Raphidocelis subcapitata, OECD 201)
Classification, Labelling, and Packaging Regulation (EC) No 1272/2008
The available experimental test data are reliable and suitable for classification purposes under Regulation (EC) No 1272/2008. The test substance was not found to be readily biodegradable under the test conditions. The most sensitive test for the aquatic compartment was the toxicity test to algae (Raphidocelis subcapitata). The test revealed a 72-hour ErC50 and ErC10 (growth rate) of 34.9 mg/L and 12.2 mg/L, respectively. The log Pow was determined to be 0.26. Based on these results, the substance is not classified for aquatic short-term (acute) toxicity, but classified for aquatic long-term (chronic) toxicity Category 3 (H412, Harmful to aquatic life with long lasting effects) according to Regulation (EC) No 1272/2008 (CLP), as amended for the fourteenth time in Regulation (EU) 2020/217.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.