2,2-Bis(2-aminopropoxy)propane

Endpoint summary

Description of key information

Short-term toxicity to fish

In a static acute toxicity test according to OECD TG 203 with Danio rerio the 96-hour LC50 of the test item was determined to be >100 mg/L (nominal).

Short-term toxicity to aquatic invertebrates

In an acute immobilisation iest according to OECD TG 202 with Daphnia magna the 48-hour EC50 of the test item was determined to be >100 mg/L (nominal).

Toxicity to aquatic algae

In an algae growth inhibition test according to OECD TG 201 with Raphidocelis subcapitata the 72-hour EC50 and EC10 for the growth rate was determined to be 34.9 and 12.2 mg/L, respectively. The 72-hour EC50 and EC10 based on biomass was found to be 16.3 and 5.1 mg/L, respectively. The 72-hour NOEC was 9.4 mg/L both for the growth rate and biomass.

Toxicity to microorganisms

Based on measured oxygen consumption values and calculated specific respiration rates, unequivocal test item effect was established at the highest examined concentration of 1000 mg/L. For demonstration of a clear dose related inhibitory effect, the concentration spacing of this pre-test was not appropriate; however the 3-hour EC50 values of the test item is < 1000 mg/L. Due to the statistically significant differences (2-Sample T-test (α=0.05)) in the comparison with the blank control and 1000 mg/L concentration values exact NOEC value could not be determined.