Registration Dossier
Registration Dossier
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EC number: 952-252-4 | CAS number: -
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The registered substance is an Alkyl phosphate and stearyl amine salts (EC = 952-252-4), mainly composed by primary alkylamines (CAS 90640-32-7, UVCB) and phosphoric acid, octadecyl ester (CAS 39471-52-8, Multi-Constituent). Both elements present a long hydrogenated (saturated) carbon chain combinaison mono/diester phosphate with primary amine (16 to 18 carbon atoms).
Two tests on terrestrial micro-organisms are available on Phosphoric acid, octadecyl ester (CAS 39471-52-8) according OECD 216 and 217 and under GLP. The test material showed no significant adverse effect on the nitrogen activity of soil microorganisms at a test concentrations of up to and including 1000 mg/kg over a 28-Day period. The most sensible effect of Phosphoric acid, octadecyl ester (CAS 39471-52-8) is the NOEC for carbon transformation in soil was determined to be NOEC = 320 mg/kg. This value is therefore considered as the worst case value for and have been used as read-across for the registered substance.
A NOEC of 1000 mg/kg dw for soil micro-organisms can be justified for Coco alkyl amine in a read across approach as well.
The worst case value, the NOEC of 320 mg/kg is then converted to the corresponding value of the salt, resulting to a NOEC of 496 mg/kg (MW of Phosphoric acid, octadecyl ester = 454,7, MW of the registered substance = 710,7 g/mol (256 g/mol Primary alkylamine salt + 454,7 g/mol Phosphoric acid, octadecyl ester)).
Key value for chemical safety assessment
- Long-term EC10 or NOEC for soil microorganisms:
- 496 mg/kg soil dw
Additional information
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